Medical application Colorimetrix: Smartphones become mobile medical devices

Mobile phone applications developed in recent years can make it easier for doctors and patients to monitor diabetes, kidney disease and urinary tract infections, and will be used in developing countries to slow down and limit the spread of infectious diseases in the future. Developed by researchers at Cambridge University, the app called Colorimetrix can be used at home, in a clinical or remote environment, to accurately perform color-based colorimetric tests, and to transfer patient medical data directly to professional medical staff. in.

Cheap and portable point-of-care diagnostics have the potential to break through the limitations of today's patient screening and achieve medical care dispersion. However, even the diagnosis of experienced health care workers can be affected by equipment deficiencies, especially in developing countries, and the development of viable diagnostic methods to overcome such difficulties can reduce the burden on health care providers.

Due to the portability, compactness and ease of use of the test kit, colorimetric testing is widely used throughout the world in medical monitoring, drug testing and various environmental analyses. A typical test strip shows the result of the change in color in the solution and determines the concentration of the solution by the depth of the color. However, it is difficult to accurately read such tests, whether at home or in a remote environment. Misreading is common and results in diagnostic or therapeutic errors. Professional laboratory instruments such as high sensitivity spectrophotometers or professional test readers can automatically analyze data, however these devices are too expensive and cumbersome.

The new Colorimetrix app makes it easy to make accurate readings of colorimetric tests, and you can do it with just one phone. The app uses the phone's camera and an algorithm to convert test data into concentration values ​​for display on the screen in seconds.

Colorimetrix, a picture of turning a smartphone into a mobile medical device

After putting urine, saliva or other body fluids into the test kit, the user simply takes the test results, app analyzes the color of the kit and compares it with the pre-made standard, and then displays the numerical results on the screen of the mobile phone. The results of the test results can be stored and sent to a health care professional or directly to the mobile phone for analysis and diagnosis.

Colorimetrix, a picture of turning a smartphone into a mobile medical device

The app can be used in home, clinical or resource-constrained environments and is compatible with Android and iOS systems. In the initial laboratory test, the app can accurately read urine sugar, protein and pH concentrations on commercial urine test strips without any external equipment. Specific details have been published in the Journals and Actuators B: Chemical.

The app is more than just a lab application, and patients can use it to monitor diabetes or as a public health device to send medical data to professionals in real time. The study's Ph.D. in chemical engineering and biotechnology, Ali YeTIsen, said the app has potential to fight AIDS, tuberculosis and dysentery in developing countries, and the concept of mobile healthcare is becoming a reality. The rapid spread of data can be sent to doctors or integrated laboratories to slow down and limit the spread of infectious diseases.

In addition to developing medical applications, researchers are planning to publicly release the app for other colorimetric tests, such as laboratory equipment, veterinary diagnostics, and environmental screening tools.

Dr Leo MarTInez, who developed the app, said that buying the app as a lab device would save clinics and research institutions. The team is planning to use the app at Addenbrooke Hospital as a clinical test for kidney function and infection.

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